Toxicoepigenetics
  • Author : Shaun D. McCullough
  • Release Date : 02 November 2018
  • Publisher : Academic Press
  • Genre : Medical
  • Pages : 428
  • ISBN 13 : 9780128124345

Toxicoepigenetics Book Summary

Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken center stage in the study of diseases such as cancer, diabetes, and neurodegeneration. Increasing the presence of epigenetics in toxicological research allows for a more in-depth understanding of important aspects of toxicology such as the role of the environment and lifestyle influencing the individual susceptibility to these effects and the trans-generational transmission of these health effects and susceptibilities. Methods chapters are included to help improve efficacy and efficiency of protocols in both the laboratory and the classroom. Toxicoepigenetics: Core Principles and Applications is an essential book for researchers and academics using epigenetics in toxicology research and study. Introduces the fundamental principles and practices for understanding the role of the epigenome in toxicology Presents the foundation of epigenetics for toxicologists with a broad range of backgrounds Discusses the incorporation of epigenetics and epigenomics into current toxicological studies and interpretation of epigenetic data in toxicological applications

Toxicoepigenetics

Toxicoepigenetics

Author : Shaun D. McCullough,Dana Dolinoy
Publisher : Academic Press
Genre : Medical
Total View : 8427 Views
File Size : 48,9 Mb
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Toxicoepigenetics: Core Principles and Applications examines the core aspects of epigenetics, including chromatin biology, DNA methylation, and non-coding RNA, as well as fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Although its integration into the field of toxicology is in its infancy, epigenetics have taken ...

Translational Toxicology and Therapeutics

Translational Toxicology and Therapeutics

Author : Michael D. Waters,Claude L. Hughes
Publisher : John Wiley & Sons
Genre : Medical
Total View : 8742 Views
File Size : 40,5 Mb
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Written by leading research scientists, this book integrates current knowledge of toxicology and human health through coverage of environmental toxicants, genetic / epigenetic mechanisms, and carcinogenicity. Provides information on lifestyle choices that can reduce cancer risk Offers a systematic approach to identify mutagenic, developmental and reproductive toxicants Helps readers develop new ...

Epigenetic Toxicology

Epigenetic Toxicology

Author : Shaun D. McCullough,Dana Dolinoy
Publisher : Academic Press
Genre : Medical
Total View : 3660 Views
File Size : 53,6 Mb
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Epigenetic Toxicology: Core Principles and Applications examines epigenetics, including chromatin biology, DNA methylation and non-coding RNA, along with fundamental techniques and considerations for studying each of these mechanisms of epigenetic regulation. Epigenetics have taken center stage in the study of diseases, such as cancer, diabetes and neurodegeneration. However, the integration ...

Pharmacoepigenetics

Pharmacoepigenetics

Author : Anonim
Publisher : Academic Press
Genre : Medical
Total View : 1094 Views
File Size : 48,9 Mb
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Pharmacoepigenetics, Volume Eleven provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the ...

Toxicology and Epigenetics

Toxicology and Epigenetics

Author : Saura C. Sahu
Publisher : John Wiley & Sons
Genre : Science
Total View : 9699 Views
File Size : 42,6 Mb
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Epigenetics is the study of both heritable and non-heritablechanges in the regulation of gene activity and expression thatoccur without an alteration in the DNA sequence. Thisdynamic and rapidly developing discipline is making its impactacross the biomedical sciences, in particular in toxicology whereepigenetic differences can mean that different individuals responddifferently to ...

Personalized Epigenetics

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Author : Trygve Tollefsbol
Publisher : Academic Press
Genre : Science
Total View : 1010 Views
File Size : 49,6 Mb
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Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and ...

Pharmacokinetics and Toxicokinetic Considerations   Vol II

Pharmacokinetics and Toxicokinetic Considerations Vol II

Author : Rakesh Kumar Tekade
Publisher : Academic Press
Genre : Business & Economics
Total View : 8758 Views
File Size : 48,9 Mb
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Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the ...