The Orexin System. Basic Science and Role in Sleep Pathology
  • Author : M.A. Steiner
  • Release Date : 28 May 2021
  • Publisher : Karger Medical and Scientific Publishers
  • Genre : Health & Fitness
  • Pages : 154
  • ISBN 13 : 9783318068443

The Orexin System. Basic Science and Role in Sleep Pathology Book Summary

The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors this research and the authors share their ideas and perspectives on the novel developments within the field. The book examines the intricate role of the orexin system in regulating sleep and wake, and its interaction with other wake-regulating systems. The orexin system is dissected at the cellular and molecular level to explore the diversity of the orexin-producing neurons, their projections, and their signaling pathways. Additionally, the book discusses the diseases which are associated with a dysfunctional orexin system, such as narcolepsy, insomnia, substance abuse, and Alzheimer’s disease, and explores the new potential therapeutic applications derived from the burst of research around this fascinating system. This publication is essential reading for neurobiologists, neurologists, psychopharmacologists, sleep researchers, and other researchers and clinical scientists interested in sleep, sleep research, insomnia, and medicine in general.

The Orexin System  Basic Science and Role in Sleep Pathology

The Orexin System Basic Science and Role in Sleep Pathology

Author : M.A. Steiner,M. Yanagisawa,M. Clozel
Publisher : Karger Medical and Scientific Publishers
Genre : Health & Fitness
Total View : 9635 Views
File Size : 54,8 Mb
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The orexin system, discovered in 1998, has emerged as a crucial player in regulating the sleep and wake balance inside our brain. This discovery has sparked a burst of novel and dynamic research on the physiology and pathology of sleep. The Orexin System: Basic Science and Role in Sleep Pathology honors ...

Hypocretins

Hypocretins

Author : Luis De Lecea,J. Gregor Sutcliffe
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 211 Views
File Size : 45,8 Mb
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The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep ...

The Orexin Hypocretin System

The Orexin Hypocretin System

Author : Seiji Nishino,Takeshi Sakurai
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 8816 Views
File Size : 49,8 Mb
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Impairment of orexin/hypocretin signaling causes narcolepsy-cataplexy in animals and humans. Most human narcolepsy-cataplexy cases are associated with orexin/hypocretin ligand deficiency, which can be detected clinically using cerebrospinal orexin/hypocretin measures and may lead to future treatments with orexin/hypocretin replacement therapy. In The Orexin/Hypocretin System: Physiology and ...

The Orexin hypocretin System

The Orexin hypocretin System

Author : Anantha Shekhar
Publisher : Elsevier
Genre : Medical
Total View : 9462 Views
File Size : 52,7 Mb
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"In The Orexin/Hypocretin System: Physiology and Pathophysiology, leading researchers and clinicians set the stage for further research on the loss of orexin/hypocretin neurons in humans, regulation of sleep and wakefulness by the orexin/hypocretin system, and the role of the orexin/hypocretin system in many other physiological processes, ...

The Orexin Hypocretin System

The Orexin Hypocretin System

Author : Jim R. Fadel,Joshua A. Burk
Publisher : Academic Press
Genre : Medical
Total View : 961 Views
File Size : 43,5 Mb
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The Orexins/Hypocretins System: Functional Roles and Therapeutic Potential summarizes research on both the physiological functioning of orexins, their impact on homeostatic processes, and related disorders. The book encompasses the effects on appetite, sleep, substance abuse, cognition, and anxiety. Additionally, it examines new therapeutic approaches utilizing orexins, including utilization of ...

Behavioral Neuroscience of Orexin Hypocretin

Behavioral Neuroscience of Orexin Hypocretin

Author : Andrew J Lawrence,Luis de Lecea
Publisher : Springer
Genre : Medical
Total View : 2905 Views
File Size : 53,5 Mb
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This issue of Current Topics in Behavioral Neuroscience focuses on the neuropeptide orexin (hypocretin) and brings together scientists from around the world who will provide a timely discussion of how this peptide regulates behavior. This is a fast-moving field, and with the incorporation of novel technologies, new breakthroughs are likely ...