Successes and Challenges of NK Immunotherapy
  • Author : Benjamin Bonavida
  • Release Date : 23 June 2021
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 538
  • ISBN 13 : 9780128243961

Successes and Challenges of NK Immunotherapy Book Summary

Successes and Challenges of NK Immunotherapy: Increasing Anti-tumor Efficacy describes the unique therapeutic applications of NK cells to fight cancers and eliminate the bulk and subset of cancer stem cells responsible for metastasis, relapse and recurrences. The book provides information on the development, engineering, mechanisms of action, response to various preclinical models, and applications in various clinical trials. Sections cover the development of highly engineered cytotoxic NK cells, their mechanisms of action, preclinical and clinical applications, the development and application of CAR-NK cells, and new NK-drug conjugates, also emphasizing that activated NK cells can target and kill highly resistant cancer stem cells. Written by the leading experts on NK immunotherapy worldwide, this is a valuable resource for researchers, clinicians and members of the biomedical field who are interested in understanding novel and efficient therapies to fight cancers. Discusses the unique developmental applications of NK immunotherapy against cancers, which differs greatly from other types of immunotherapies Provides up-to-date and highly relevant information through chapters written by the leading researchers in the field Presents a significant number of schematic diagrams for easy understanding and reproducibility

Successes and Challenges of NK Immunotherapy

Successes and Challenges of NK Immunotherapy

Author : Benjamin Bonavida,Anahid Jewett
Publisher : Academic Press
Genre : Science
Total View : 4377 Views
File Size : 49,6 Mb
Get Book

Successes and Challenges of NK Immunotherapy: Increasing Anti-tumor Efficacy describes the unique therapeutic applications of NK cells to fight cancers and eliminate the bulk and subset of cancer stem cells responsible for metastasis, relapse and recurrences. The book provides information on the development, engineering, mechanisms of action, response to various ...

NK Immunotherapy  Success and Challenges

NK Immunotherapy Success and Challenges

Author : Maverick Davies
Publisher : Unknown
Genre : Uncategorized
Total View : 1847 Views
File Size : 49,5 Mb
Get Book

Natural killer cells (NK cells) are the lymphocytes which belong to the same family as B and T cells, because they differentiate from a common progenitor. These cells detect and control early signs of cancer, and also recognize and kill virally infected cells. Specialized natural killer cells are found in ...

NK Cells in Cancer Immunotherapy  Successes and Challenges

NK Cells in Cancer Immunotherapy Successes and Challenges

Author : Anahid Jewett
Publisher : Academic Press
Genre : Science
Total View : 5133 Views
File Size : 41,7 Mb
Get Book

NK cells in cancer immunotherapy: Successes and Challenges explains the latest immunotherapeutic strategies focusing on NK cells to allow the best and precise combination treatment to be offered to cancer patients. It provides existing background knowledge in the field of immunotherapy and discusses the future areas of research required to ...

NK Cell Based Cancer Immunotherapy

NK Cell Based Cancer Immunotherapy

Author : Francisco Borrego,Susana Larrucea,Rafael Solana,Raquel Tarazona
Publisher : Frontiers Media SA
Genre : Immunologic diseases. Allergy
Total View : 4264 Views
File Size : 45,9 Mb
Get Book

Natural killer (NK) cells are innate lymphoid cells that have a significant role in regulating the defenses against cancer development and certain viral infections. They are equipped with an array of activating and inhibitory receptors that stimulate or diminish NK cell activity, respectively. Inhibitory receptors include, among others, the MHC ...

Basics of Chimeric Antigen Receptor  CAR  Immunotherapy

Basics of Chimeric Antigen Receptor CAR Immunotherapy

Author : Mumtaz Y. Balkhi
Publisher : Academic Press
Genre : Medical
Total View : 7115 Views
File Size : 40,5 Mb
Get Book

Basics of Chimeric Antigen Receptor (CAR) Immunotherapy presents the latest on how T cell adoptive immunotherapy has progressed in its ultimate goal of curing metastatic malignant cancers. Recent clinical data obtained with checkpoint receptor blockade inhibitors and chimeric antigen receptor (CAR) therapy has been especially promising, thus generating renewed hope ...

Natural Killer Cells

Natural Killer Cells

Author : Michael T. Lotze,Angus W. Thomson
Publisher : Academic Press
Genre : Medical
Total View : 2585 Views
File Size : 50,8 Mb
Get Book

Natural Killer Cells explains the importance of killer cells and how they are produced. It mentions that the most likely explanation for killer cell production is that they serve as a complementary system for T cells as a primary defense against viruses. However, these cells defend against certain viruses only, ...

Global Epidemiology of Cancer

Global Epidemiology of Cancer

Author : Jahangir Moini,Nicholas G. Avgeropoulos,Craig Badolato
Publisher : John Wiley & Sons
Genre : Medical
Total View : 7047 Views
File Size : 45,6 Mb
Get Book

GLOBAL EPIDEMIOLOGY OF CANCER Cancer is the second highest cause of death in the United States, and a leading cause of death globally. Our goals are to discuss the global epidemiology of various cancers, with detailed information on their prevalence, incidence, and clinical considerations. Epidemiology is the key to understanding ...