Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms
  • Author : Loutfy H. Madkour
  • Release Date : 27 June 2020
  • Publisher : Academic Press
  • Genre : Medical
  • Pages : 780
  • ISBN 13 : 9780128224960

Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms Book Summary

Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of environmental heavy metal ions and free radicals on macromolecules cells organisms, heavy metals?induced cell responses, oxidative stress, the source of oxidants, and the roles of ROS, oxidative stress and oxidative damage mechanisms. It also examines the nanotoxicity, cytotoxicity and genotoxicity mechanisms of nanomaterials and the effects of nanoparticle interactions. Antioxidant defense therapy and strategies for treatment round out the book, making it an ideal resource for researchers and professional scientists in toxicology, environmental chemistry, environmental science, nanomaterials and the pharmaceutical sciences. Covers the ecotoxicology of environmental heavy metal ions and the interactions between specific heavy metals?induced cell responses and oxidative stress Provides a better understanding of the mechanism of nanomaterial-induced toxicity as a first defense for hazard prevention Covers recent advances in new nanomedication technologies for the effects of NPs on oxidative stress, ROS and ER stress Discusses the effects of interactions between antioxidant defense therapy, ROS and strategies for treatment

Reactive Oxygen Species  ROS   Nanoparticles  and Endoplasmic Reticulum  ER  Stress Induced Cell Death Mechanisms

Reactive Oxygen Species ROS Nanoparticles and Endoplasmic Reticulum ER Stress Induced Cell Death Mechanisms

Author : Loutfy H. Madkour
Publisher : Academic Press
Genre : Medical
Total View : 2601 Views
File Size : 47,7 Mb
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Reactive Oxygen Species (ROS), Nanoparticles, and Endoplasmic Reticulum (ER) Stress-Induced Cell Death Mechanisms presents the role of ROS?mediated pathways cellular signaling stress, endoplasmic reticulum (ER) stress, oxidative stress, oxidative damage, nanomaterials, and the mechanisms by which metalloids and nanoparticles induce their toxic effects. The book covers the ecotoxicology of ...

Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

Author : Loutfy H. Madkour
Publisher : Unknown
Genre : Nanoparticles
Total View : 3005 Views
File Size : 49,8 Mb
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This book provides insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. It presents the recent advances in new nanomedication technologies of the effects of nanoparticles NPs on oxidative stress, RONS ...

Nanoparticle Based Drug Delivery in Cancer Treatment

Nanoparticle Based Drug Delivery in Cancer Treatment

Author : Loutfy H. Madkour
Publisher : CRC Press
Genre : Science
Total View : 5630 Views
File Size : 45,9 Mb
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The careful choice of nanoparticles as targets and in drug delivery routes enhances therapeutic efficacy in cancer. Nanoparticle-Based Drug Delivery in Cancer Treatment discusses nanotechnological developments of interfering RNA-based nanoparticles, delivery vehicles, and validated therapeutic RNAi–molecular target interactions and explains the results of clinical and preclinical trials. The book ...

Handbook of Oxidative Stress in Cancer  Therapeutic Aspects

Handbook of Oxidative Stress in Cancer Therapeutic Aspects

Author : Sajal Chakraborti
Publisher : Springer Nature
Genre : Medical
Total View : 4066 Views
File Size : 50,8 Mb
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This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox ...

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RNA Delivery Function for Anticancer Therapeutics

Author : Loutfy H. Madkour
Publisher : CRC Press
Genre : Science
Total View : 6993 Views
File Size : 40,8 Mb
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This book presents an overview of the current status of translating the RNAi cancer therapeutics in the clinic, a brief description of the biological barriers in drug delivery, and the roles of imaging in aspects of administration route, systemic circulation, and cellular barriers for the clinical translation of RNAi cancer ...

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Emerging Nanomaterials for Advanced Technologies

Author : Anand Krishnan
Publisher : Springer Nature
Genre : Electronic books
Total View : 3626 Views
File Size : 43,9 Mb
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Over the past decade the world has seen the rise of the fascinating and diverse field currently recognized as nanotechnology. This book covers a broad spectrum of topics within nanotechnology, including synthesis techniques, various innovative characterization techniques, growth mechanisms of nanomaterials, the physics and chemistry of nanomaterials, diverse functionalization methods, ...

Oxidative Stress in Heart Diseases

Oxidative Stress in Heart Diseases

Author : Sajal Chakraborti,Naranjan S Dhalla,Nirmal K Ganguly,Madhu Dikshit
Publisher : Springer Nature
Genre : Science
Total View : 9165 Views
File Size : 53,8 Mb
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This book bridges the gap between fundamental and translational research in the area of heart disease. It describes a multidisciplinary approach, and demonstrates biochemical mechanisms associated with dysregulation of redox signaling, which leads heart disease. Presenting recent studies on improved forms of ROS scavenging enzymes; specific inhibitors for different ROS ...

The JNK Signaling Pathway

The JNK Signaling Pathway

Author : Anning Lin
Publisher : CRC Press
Genre : Science
Total View : 1654 Views
File Size : 43,9 Mb
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Signal transduction is one of the most exciting research areas in modern biology as it deals with how information flows from the extracellular environment into a living cell to change its metabolism, genotype and phenotype. With the completion of the genomes of human and several other species, it becomes even ...