Post-Genomic Cardiology
  • Author : José Marín-García
  • Release Date : 09 May 2014
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 944
  • ISBN 13 : 9780124046429
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Post-Genomic Cardiology Book Summary

In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive understanding of the many mutations that underlie cardiovascular diseases and adverse drug reactions is within our reach. This book, written by respected cardiologist José Marín-García, features discussion on the Hap-Map: the largest international effort to date aiming to define the differences between our individual genomes. This unique reference further reviews and investigates genome sequences from our evolutionary relatives that could help us decipher the signals of genes, and offers a comprehensive and critical evaluation of regulatory elements from the complicated network of the background DNA. Offers updated discussion of cutting-edge molecular techniques including new genomic sequencing / NGS / Hap-Map / bioinformatics / systems biology approaches Analyzes mitochondria dynamics and their role in cardiac dysfunction, up-to-date analysis of cardio-protection, and cardio-metabolic syndrome Presents recent translational studies, gene therapy, transplantation of stem cells, and pharmacological treatments in CVDs

Post Genomic Cardiology

Post Genomic Cardiology

Author : José Marín-García
Publisher : Academic Press
Genre : Science
Total View : 1999 Views
File Size : 55,8 Mb
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In this second edition of Post-Genomic Cardiology, developing and new technologies such as translational genomics, next generation sequencing (NGS), bioinformatics, and systems biology in molecular cardiology are assessed in light of their therapeutic potential. As new methods of mutation screening emerge, both for the genome and for the “epigenome,” comprehensive ...

Aging and the Heart

Aging and the Heart

Author : José Marín-García
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 8691 Views
File Size : 53,9 Mb
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In this book, the genetic and molecular basis of cardiovascular aging is examined in detail and a comprehensive assessment given of the bioenergetics changes occurring in human and animal models of cardiac aging. Both current diagnostic and future therapeutic modalities are presented, giving this book a dual-pronged approach. Cardiac aging, ...

Heart Failure

Heart Failure

Author : José Marín-García
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 7240 Views
File Size : 44,5 Mb
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Heart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease. An authoritative contribution to the field, this book provides a detailed description of ...

Signaling in the Heart

Signaling in the Heart

Author : José Marín-García
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 4085 Views
File Size : 53,8 Mb
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Signal transduction pathways are at the core of most biological processes and are critical regulators of heart physiology and pathophysiology. The heart is both a transmitter and dynamic receptor of a variety of intracellular and extracellular stimuli, playing a critical role of an integrator of diverse signaling mechanisms. Alterations in ...

Cardiovascular Genomics

Cardiovascular Genomics

Author : Mohan K. Raizada,Julian F. R. Paton,Michael J. Katovich,Sergey Kasparov
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 8215 Views
File Size : 40,5 Mb
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Recognized scientists and clinicians from around the world discuss the most recent molecular approaches to understanding the cardiovascular system in both health and disease. The authors focus on all components of the system, including blood vessels, heart, kidneys, and the brain, and cover disease states ranging from vascular and cardiac ...

Proteomic and Genomic Analysis of Cardiovascular Disease

Proteomic and Genomic Analysis of Cardiovascular Disease

Author : Jennifer E. Van Eyk,Michael J. Dunn
Publisher : Wiley-Blackwell
Genre : Science
Total View : 8755 Views
File Size : 43,7 Mb
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This is the very first book to focus on this new approach that will eventually aid in developing new diagnostic markers and therapies for controlling and treating heart disease - the number-one killer in the industrialized world. Divided into two parts, the book describes not only the potentials, but also ...