Pharmaceutical Applications of Dendrimers
  • Author : Hitesh Kulhari
  • Release Date : 15 November 2019
  • Publisher : Elsevier
  • Genre : Uncategorized
  • Pages : 500
  • ISBN 13 : 0128145277

Pharmaceutical Applications of Dendrimers Book Summary

Dendrimers are engineered nano-sized macromolecule with a high degree of molecular uniformity, narrow size distribution, tunable size, multivalency and high surface functionality. These favourable characteristics make dendrimers effective drug delivery carriers. As a result, dendrimers have demonstrated wide applicability in nanopharmaceuticals Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in solubilisation of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. Dendrimers have been successfully used as a solubility enhancer and drug delivery carrier. Dendrimer-based formulations have also been used for transfection or gene delivery. Diagnostic applications of dendrimers include MRI contrast agent and imaging of diseased areas. In addition, dendrimers such as PPI and PAMAM are reported to possess anti-inflammatory, antimicrobial and antiviral activities. In past five years, photosensitizers such as rose Bengal and protoporphyrin IX have also been delivered using PAMAM and PPI dendrimers for the treatment of cancer. These important and emerging uses are discussed here in detail. This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery. Explores the role of dendrimers in the design of dendritic nanoplateforms for targeted drug and gene delivery systems Discusses the potential of dendrimers in preformulation and formulation development Addresses the clinical and regulatory challenges in the development of dendrimer-based formulations

Pharmaceutical Applications of Dendrimers

Pharmaceutical Applications of Dendrimers

Author : Hitesh Kulhari,Abhay Singh Chauhan
Publisher : Elsevier
Genre : Uncategorized
Total View : 7735 Views
File Size : 50,8 Mb
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Dendrimers are engineered nano-sized macromolecule with a high degree of molecular uniformity, narrow size distribution, tunable size, multivalency and high surface functionality. These favourable characteristics make dendrimers effective drug delivery carriers. As a result, dendrimers have demonstrated wide applicability in nanopharmaceuticals Pharmaceutical Applications of Dendrimers explores the applications of dendrimers ...

Dendrimer Based Nanotherapeutics

Dendrimer Based Nanotherapeutics

Author : Prashant Kesharwani
Publisher : Academic Press
Genre : Business & Economics
Total View : 2645 Views
File Size : 55,7 Mb
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Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, ...

Dendrimers for Drug Delivery

Dendrimers for Drug Delivery

Author : Anil K. Sharma,Raj K. Keservani
Publisher : CRC Press
Genre : Medical
Total View : 8765 Views
File Size : 40,7 Mb
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With chapters from highly skilled, experienced, and renowned scientists and researchers from around the globe, Dendrimers for Drug Delivery provides an abundance of information on dendrimers and their applications in the field of drug delivery. The volume begins with an introduction to dendrimers, summarizing dendrimer applications and the striking features ...

Pharmaceutical Applications of Dendrimers

Pharmaceutical Applications of Dendrimers

Author : Abhay Singh Chauhan,Hitesh Kulhari
Publisher : Elsevier
Genre : Technology & Engineering
Total View : 8196 Views
File Size : 45,6 Mb
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Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the ...

Nanoparticles in Pharmacotherapy

Nanoparticles in Pharmacotherapy

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Genre : Medical
Total View : 2056 Views
File Size : 48,9 Mb
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Nanoparticles in Pharmacotherapy explores the most recent findings on how nanoparticles are used in pharmacotherapy, starting with their synthesis, characterization and current or potential uses. This book is a valuable resource of recent scientific progress that includes the most cutting-edge applications of nanoparticles in pharmacotherapy. It is ideal for researchers, ...

Dendrimers in Biomedical Applications

Dendrimers in Biomedical Applications

Author : Barbara Klajnert,Ling Peng,Valentin Cena
Publisher : Royal Society of Chemistry
Genre : Technology & Engineering
Total View : 2694 Views
File Size : 47,6 Mb
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Dendrimers are important molecules that are currently undergoing investigation for use in a variety of different biomedical applications. This book explores the use of dendrimers for a variety of potential functions, including antiamyloidogenic agents, drug delivery systems, nucleic acid and RNA delivery vectors and to produce hybrid fibre platforms for ...

Dendrimers in Medicine

Dendrimers in Medicine

Author : Barbara Klajnert,Maria Bryszewska
Publisher : Nova Science Pub Incorporated
Genre : Medical
Total View : 3205 Views
File Size : 53,6 Mb
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The dendrimer is a common name of polymers which are characterised by a specific structure, although their chemical composition can be very different. Dendrimers display several characteristics which distinguish them from linear polymers. All dendrimers are synthesised by attaching branched monomers to the central core molecule. Monomers are attached layer ...

Dendrimer Based Drug Delivery Systems

Dendrimer Based Drug Delivery Systems

Author : Yiyun Cheng
Publisher : John Wiley & Sons
Genre : Medical
Total View : 8648 Views
File Size : 53,7 Mb
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The opportunities and challenges of using dendrimers to improvedrug delivery Among pharmaceutical and biomedical researchers, the use ofdendrimers in drug delivery systems has attracted increasinginterest. In particular, researchers have noted that the volume ofa dendrimer increases when it has a positive charge. If thisproperty can be applied effectively, dendrimers have ...