Neuroprotection in Alzheimer's Disease
  • Author : Illana Gozes
  • Release Date : 30 December 2016
  • Publisher : Academic Press
  • Genre : Medical
  • Pages : 342
  • ISBN 13 : 9780128037126

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Book Description: Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together the latest findings, both basic, and clinical, under the same cover, making it easy for the reader to obtain a complete overview of the state-of-the-field and beyond. Alzheimer's disease is the most common form of dementia, accounting for 60 to 80 percent of dementia cases. It is a progressive brain disease that slowly destroys memory, thinking skills, and eventually, even the ability to carry out the simplest tasks. It is characterized by death of synapses coupled to death nerve cells and brain degeneration which is manifested by loss of cognitive abilities. Understanding neuroprotection in Alzheimer’s disease will pave the path to better disease management and novel therapeutics. Comprehensive reference detailing neuroprotection in Alzheimer’s Disease, with details on nerve cell protection and new advances in disease management Combines the knowledge and points-of-view of both medical doctors and basic scientists, putting the subject at the forefront for further clinical development Edited by one of the leading researchers in Alzheimer’s Disease

Neuroprotection in Alzheimer s Disease

Neuroprotection in Alzheimer s Disease

Author : Illana Gozes
Publisher : Academic Press
Genre : Medical
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Neuroprotection in Alzheimer’s Disease offers a translational point-of-view from both basic and clinical standpoints, putting it on the cusp for further clinical development with its emphasis on nerve cell protection, including the accumulation of knowledge from failed clinical trials and new advances in disease management. This book brings together ...

Neuroprotection in Autism  Schizophrenia and Alzheimer s Disease

Neuroprotection in Autism Schizophrenia and Alzheimer s Disease

Author : Illana Gozes,Joseph Levine
Publisher : Academic Press
Genre : Uncategorized
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Some shared pathophysiological mechanisms underlie autism, schizophrenia/mood disorders and Alzheimer's disease, i.e. neurodevelopmental disorders, neuropsychiatric diseases and neurodegenerative disorders. With the rapid advancement of molecular genetics including single cell analysis and detailed molecular characteristics, scientists have the opportunity to follow up on novel mechanistic aspects and offer a ...

Neuroprotection

Neuroprotection

Author : Matilde Otero-Losada,Francisco Capani,Santiago Perez Lloret
Publisher : BoD – Books on Demand
Genre : Medical
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Neurological disease affects nearly 25%–30% of the world’s population, exerting enormous financial strain on the healthcare system. Estimated current costs are around $800 annual billion, and this number is expected to increase exponentially as the global population ages. As such, new and alternative neuroprotective strategies are urgently needed. This book examines ...

Alzheimer   s Disease

Alzheimer s Disease

Author : Ralph W. Richter,Brigitte Zoeller Richter
Publisher : Springer Science & Business Media
Genre : Medical
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Alzheimer’s disease (AD) is a devastating and dehumanizing illness affecting increasingly large numbers of elderly and even middle-aged persons in a worldwide epidemic. Alzheimer’s Disease: A Physician’s Guide to Practical Management was written by selected clinicians and scientists who represent some of the world’s leading centers ...

Molecular Mechanisms and Therapeutic Strategies in Alzheimer s Disease

Molecular Mechanisms and Therapeutic Strategies in Alzheimer s Disease

Author : Veer Gupta,Vivek Gupta
Publisher : LAP Lambert Academic Publishing
Genre : Uncategorized
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This book provides an insight into the mechanism on the role of amino acid stereospecificity based amyloid beta aggregation pattern; non-apoptotic amyloid beta peptide induced DNA nicking and neuro-neutraceutical property of garlic and curcumin derivatives. These findings provide a molecular understanding of the neurodegeneration and neuroprotection in Alzheimers Disease brain. ...

Neuroprotective Natural Products

Neuroprotective Natural Products

Author : Goutam Brahmachari
Publisher : John Wiley & Sons
Genre : Medical
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Focusing on the molecular mechanisms of powerful naturally occurring agents and their implication for drug discovery, this timely book presents an overview of the most recent research advances in the field of bioactive natural products and natural drug formulations to combat today's destructive diseases. To this extent, the authors discuss ...

Nicotinic Acetylcholine Receptor Signaling in Neuroprotection

Nicotinic Acetylcholine Receptor Signaling in Neuroprotection

Author : Shun Shimohama,Akinori Akaike,Yoshimi Misu
Publisher : Unknown
Genre : Medical
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This open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal ...

The Handbook of Alzheimer s Disease and Other Dementias

The Handbook of Alzheimer s Disease and Other Dementias

Author : Andrew E. Budson,Neil W. Kowall
Publisher : John Wiley & Sons
Genre : Psychology
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The reference is a broad-ranging review of Alzheimer's disease and other dementias from both basic and clinical neuroscience perspectives; it provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances. Brings the reader up-to-date with cutting-edge developments in this exciting and fast-paced field ...

Nutrition and Cancer Prevention

Nutrition and Cancer Prevention

Author : American Institute for Cancer Research
Publisher : Springer Science & Business Media
Genre : Medical
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Recent advances have contributed to our understanding of how a plant-based diet confers many health advantages and how substances from plants may be effective in the prevention of specific cancers. The Ninth Annual Research Conference of the American Institute for Cancer Research has focused on the latest developments in several ...

Neuroprotection in Autism  Schizophrenia and Alzheimer s disease

Neuroprotection in Autism Schizophrenia and Alzheimer s disease

Author : Illana Gozes,Joseph Levine
Publisher : Academic Press
Genre : Medical
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Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview on recent clinical studies and the similarities discovered in the most prevalent brain disorders. The book's content will help shed light on basic mechanisms and provide new avenues for early diagnosis toward disease prevention and disease modification. It is ...

Oxidative Stress and Neurodegenerative Disorders

Oxidative Stress and Neurodegenerative Disorders

Author : G. Ali Qureshi,S. Hasan Parvez
Publisher : Elsevier
Genre : Science
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Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species. Brain cells are continuously exposed to reactive oxygen species generated by oxidative metabolism, and in certain pathological conditions defense mechanisms against oxygen radicals may be weakened and/or ...

Alzheimer s Disease

Alzheimer s Disease

Author : Jolanta Dorszewska,Wojciech Kozubski
Publisher : BoD – Books on Demand
Genre : Medical
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Alzheimer's disease was discovered over 100 years ago and still belongs to incurable neurological diseases; its pharmacotherapy is considered to be ineffective. This book presents contemporary views on the genetic, biochemical, and immunological determinants of this disease. This book also concerns the issue of Alzheimer's disease prevention through lifestyle and physical ...

Neurodegenerative Diseases

Neurodegenerative Diseases

Author : Uday Kishore
Publisher : BoD – Books on Demand
Genre : Medical
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This book highlights the pathophysiological complexities of the mechanisms and factors that are likely to be involved in a range of neuroinflammatory and neurodegenerative diseases including Alzheimer's disease, other Dementia, Parkinson Diseases and Multiple Sclerosis. The spectrum of diverse factors involved in neurodegeneration, such as protein aggregation, oxidative stress, caspases ...

Hormones  Cognition and Dementia

Hormones Cognition and Dementia

Author : Eef Hogervorst,Victor W. Henderson,Robert B. Gibbs,Roberta Diaz Brinton
Publisher : Cambridge University Press
Genre : Medical
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A decade ago, oestrogen-containing hormone therapy was viewed as a promising strategy for the prevention and treatment of dementia and age-related cognitive decline. However, treatment trials in women with Alzheimer's disease showed that oestrogens did not reverse cognitive impairment, and clinical trials in healthy older women indicated that oestrogens did ...