Molecular and Genetic Basis of Renal Disease
  • Author : David B. Mount
  • Release Date : 06 October 2022
  • Publisher : Elsevier Health Sciences
  • Genre : Medical
  • Pages : 582
  • ISBN 13 : 9781416002529

Molecular and Genetic Basis of Renal Disease Book Summary

This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron as well as the most common genetic and acquired renal diseases. A comprehensive clinical review of Medelian renal disease is also be included. Detailed review of the molecular anatomy and pathophysiology of the nephron that provides relevant basic science to consider when diagnosing and managing patients with these disorders.

Molecular and Genetic Basis of Renal Disease

Molecular and Genetic Basis of Renal Disease

Author : David B. Mount,Martin R. Pollak
Publisher : Elsevier Health Sciences
Genre : Medical
Total View : 7252 Views
File Size : 55,6 Mb
Get Book

This companion to Brenner and Rector's The Kidney offers a state-of-the-art summary of the most recent advances in renal genetics. Molecular and Genetic Basis for Renal Disease provides the nephrologist with a comprehensive look at modern investigative tools in nephrology research today, and reviews the molecular pathophysiology of the nephron ...

The Kidney

The Kidney

Author : Peter D. Vize,Adrian S. Woolf,Jonathan B.L. Bard
Publisher : Elsevier
Genre : Science
Total View : 2426 Views
File Size : 53,9 Mb
Get Book

Organogenesis of the kidney has been intensely studied for over a century. In recent years advances in molecular techniques have not only made great inroads into exploring the genetic regulation of this complex process but also began to unravel the molecular basis of many forms of congenital kidney disease. This ...

Genetics of Kidney Diseases

Genetics of Kidney Diseases

Author : Harvest F. Gu,Martin H. De Borst
Publisher : Frontiers Media SA
Genre : Uncategorized
Total View : 2355 Views
File Size : 41,5 Mb
Get Book

...

Genetics of Bone Biology and Skeletal Disease

Genetics of Bone Biology and Skeletal Disease

Author : R. V. Thakker
Publisher : Academic Press
Genre : Medical
Total View : 1409 Views
File Size : 43,6 Mb
Get Book

This book identifies and analyzes the genetic basis of bone disorders in humans and demonstrates the utility of mouse models in furthering the knowledge of mechanisms and evaluations of treatments. The book is aimed at all students of bone biology and genetics, and with this in mind, it includes general ...

Genetic Diseases of the Kidney

Genetic Diseases of the Kidney

Author : Richard P. Lifton,Stefan Somlo,Gerhard H. Giebisch,Donald W. Seldin
Publisher : Academic Press
Genre : Science
Total View : 3679 Views
File Size : 54,7 Mb
Get Book

Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the ...

Genetics for Rheumatologists

Genetics for Rheumatologists

Author : Matthew A. Brown,Matthew Brown,Julia L. Newton,B. Paul Wordsworth
Publisher : Remedica
Genre : Medical
Total View : 2245 Views
File Size : 40,7 Mb
Get Book

Annotation Trainee and practicing rheumatologists The study of disease genetics arguably began in rheumatology, with the description of the hereditary basis of alkaptonuria by Garrod in 1902, and the introduction of the concept of in-born errors of metabolism. A large proportion of the diseases seen by rheumatologists have genetic influences. The ...

Cystogenesis

Cystogenesis

Author : Jong Hoon Park,Curie Ahn
Publisher : Springer
Genre : Medical
Total View : 7363 Views
File Size : 52,7 Mb
Get Book

Autosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor ...

Small Molecule Therapy for Genetic Disease

Small Molecule Therapy for Genetic Disease

Author : Jess G. Thoene
Publisher : Cambridge University Press
Genre : Medical
Total View : 6138 Views
File Size : 55,9 Mb
Get Book

Thoene summarises the substantial work that has been accomplished in the treatment of inborn errors of metabolism with simple molecules. This handbook will enable interested clinician scientists to rapidly survey the field, thus ascertaining what has been done as well as future directions for therapeutic research. Its important introductory chapters ...