Improving the Therapeutic Ratio in Head and Neck Cancer
  • Author : Anonim
  • Release Date : 04 October 2019
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 376
  • ISBN 13 : 9780128178690

Improving the Therapeutic Ratio in Head and Neck Cancer Book Summary

Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites. Provides key scientific background for clinicians when developing novel clinical trials and important examples for basic scientists of the types of work required to move a concept from the lab to the clinic Presents consistent pathway diagrams in each chapter, thus making it easier to understand complicated pathways Includes chapter summaries of the critical next steps needed to move studies from their current state into practice changing clinical data

Improving the Therapeutic Ratio in Head and Neck Cancer

Improving the Therapeutic Ratio in Head and Neck Cancer

Author : Anonim
Publisher : Academic Press
Genre : Science
Total View : 4229 Views
File Size : 53,9 Mb
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Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical ...

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Publisher : Springer
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Total View : 9232 Views
File Size : 50,5 Mb
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Non-melanoma skin cancer is a global public health issue. With an ever-increasing, and ageing, world population coupled with increasing numbers of immunosuppressed individuals the number of patients continues to rise. The head and neck is overwhelmingly the most frequent location for the development of a non-melanoma skin cancer and as ...