Genome Engineering via CRISPR-Cas9 System
  • Author : Vijai Singh
  • Release Date : 18 February 2020
  • Publisher : Academic Press
  • Genre : Science
  • Pages : 384
  • ISBN 13 : 9780128181416

Genome Engineering via CRISPR-Cas9 System Book Summary

Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can be designed, used and applied. However, it is not easy to find relevant information gathered in a single source. The book contains a wide range of applications of CRISPR in research of bacteria, virus, algae, plant and mammalian and also discusses the modeling of drosophila, zebra fish and protozoan, among others. Other topics covered include diagnosis, sensor and therapeutic applications, as well as ethical and regulatory issues. This book is a valuable source not only for beginners in genome engineering, but also researchers, clinicians, stakeholders, policy makers, and practitioners interested in the potential of CRISPR-Cas9 in several fields. Provides basic understanding and a clear picture on how to design, use and implement the CRISPR-Cas9 system in different organisms Explains how to create an animal model for disease research and screening purposes using CRISPR Discusses the application of CRISPR-Cas9 systems in basic sciences, biomedicine, virology, bacteriology, molecular biology, neurology, cancer, industry, and many more

Genome Engineering via CRISPR Cas9 System

Genome Engineering via CRISPR Cas9 System

Author : Vijai Singh,Pawan K. Dhar
Publisher : Academic Press
Genre : Science
Total View : 8516 Views
File Size : 48,7 Mb
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Genome Engineering via CRISPR-Cas9 Systems presents a compilation of chapters from eminent scientists from across the globe who have established expertise in working with CRISPR-Cas9 systems. Currently, targeted genome engineering is a key technology for basic science, biomedical and industrial applications due to the relative simplicity to which they can ...

Chromosomal Mutagenesis

Chromosomal Mutagenesis

Author : Shondra M. Pruett-Miller
Publisher : Humana Press
Genre : Medical
Total View : 978 Views
File Size : 44,7 Mb
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This new edition explores current and emerging mutagenesis methods focusing specifically on mammalian systems and commonly used model organisms through comprehensive coverage and detailed protocols. Since the first edition, major advances and discoveries have made chromosomal mutagenesis a widely used technique and one that is available to any molecular biology ...

CRISPR Cas Systems

CRISPR Cas Systems

Author : Rodolphe Barrangou,John van der Oost
Publisher : Springer Science & Business Media
Genre : Science
Total View : 1866 Views
File Size : 55,6 Mb
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CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have ...

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Genome Editing and Engineering

Author : Krishnarao Appasani
Publisher : Cambridge University Press
Genre : Science
Total View : 9957 Views
File Size : 48,5 Mb
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A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment....

Targeted Genome Editing Using Site Specific Nucleases

Targeted Genome Editing Using Site Specific Nucleases

Author : Takashi Yamamoto
Publisher : Springer
Genre : Science
Total View : 5683 Views
File Size : 43,5 Mb
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This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genome editing tools are then described in detail, in iPS cells and diverse organisms such as mice, rats, marine invertebrates, fish, frogs, ...

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Author : Yuan-Chuan Chen,Shiu-Jau Chen
Publisher : BoD – Books on Demand
Genre : Medical
Total View : 1813 Views
File Size : 41,5 Mb
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Gene-editing technologies (e.g., ZFNs, TALENs, and CRISPRs/Cas9) have been extensively used as tools in basic research. They are further applied in manufacturing agricultural products, food, industrial products, medicinal products, etc. Particularly, the discovery of medicinal products using gene-editing technologies will open a new era for human therapeutics. Though ...

Engineering Efficient and Safe in Situ Genome Regulation Via CRISPR Cas9 for Enabling Gene Therapies

Engineering Efficient and Safe in Situ Genome Regulation Via CRISPR Cas9 for Enabling Gene Therapies

Author : Ana Maria Moreno
Publisher : Unknown
Genre : Uncategorized
Total View : 4910 Views
File Size : 44,6 Mb
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While the genetic and pathogenic basis of human diseases continues to grow, translation is currently bottlenecked by lack of tools and technologies to administer and evaluate corresponding gene-based therapeutics. Consequently, development of safe and efficient in vivo gene transfer platforms, coupled with emerging genome and epigenome engineering tools, will transform ...

CRISPR  Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

CRISPR Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases

Author : Luis María Vaschetto
Publisher : CRC Press
Genre : Mathematics
Total View : 7946 Views
File Size : 55,6 Mb
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The CRISPR-Cas9 genome-editing system is creating a revolution in the science world. In the laboratory, CRISPR-Cas9 can efficiently be used to target specific genes, correct mutations and regulate gene expression of a wide array of cells and organisms, including human cells. CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders ...