Genome Chaos
  • Author : Henry H. Heng
  • Release Date : 25 May 2019
  • Publisher : Academic Press
  • Genre : Medical
  • Pages : 556
  • ISBN 13 : 9780128136362

Genome Chaos Book Summary

Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this thought-provoking text, Dr. Heng invigorates fresh discussions in genome theory and helps readers reevaluate their current understanding of human genetics, evolution, and new pathways for advancing molecular and precision medicine. Bridges basic research and clinical application and provides a foundation for re-examining the results of large-scale omics studies and advancing molecular medicine Gathers the most pressing questions in genomic and cytogenomic research Offers alternative explanations to timely puzzles in the field Contains eight evidence-based chapters that discuss 4d-genomics, genes and genomes as distinct biological entities, genome chaos and macro-cellular evolution, evolutionary cytogenetics and cancer, chromosomal coding and fuzzy inheritance, and more

Genome Chaos

Genome Chaos

Author : Henry H. Heng
Publisher : Academic Press
Genre : Medical
Total View : 7311 Views
File Size : 52,8 Mb
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Genome Chaos: Rethinking Genetics, Evolution, and Molecular Medicine transports readers from Mendelian Genetics to 4D-genomics, building a case for genes and genomes as distinct biological entities, and positing that the genome, rather than individual genes, defines system inheritance and represents a clear unit of selection for macro-evolution. In authoring this ...

Intratumor Diversity and Clonal Evolution in Cancer

Intratumor Diversity and Clonal Evolution in Cancer

Author : David Gisselsson
Publisher : Academic Press
Genre : Medical
Total View : 7252 Views
File Size : 51,8 Mb
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This specialized volume of Advances in Cancer Research is dedicated to the complex and largely unexplored field of intratumor diversity, with respect to differences in both genotype and phenotype among cell populations within tumors. Unique subject matter: there are relatively few previous publications covering this complex topic, even though it ...

Debating Cancer

Debating Cancer

Author : Henry H Heng
Publisher : World Scientific
Genre : Science
Total View : 6444 Views
File Size : 41,9 Mb
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Cancer research is at a crossroads. Traditionally, cancer has been thought of as a disease of gene mutation, where the stepwise accumulation of cancer gene mutations is the key, and the identification of common gene mutations has been considered to be essential for diagnosis and treatment. Despite extensive research efforts ...

Human Interphase Chromosomes

Human Interphase Chromosomes

Author : Yuri B. Yurov,Svetlana G. Vorsanova,Ivan Y. Iourov
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 9467 Views
File Size : 42,5 Mb
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This title will focus on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and human genome function in interphase nuclei at the chromosomal level have been repeatedly shown to play a significant role in a variety of basic biological processes involved in realization ...

Embracing Complexity in Health

Embracing Complexity in Health

Author : Joachim P. Sturmberg
Publisher : Springer
Genre : Medical
Total View : 7887 Views
File Size : 51,6 Mb
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This detailed volume illustrates the transformative nature of systems and complexity sciences for practice, research, education, and health system organization. Researchers highlight the fresh perspectives and novel approaches offered by these interdisciplinary fields in addressing the complexities of global, national, and community health challenges in the 21st century. With the ...

Ecology and Evolution of Cancer

Ecology and Evolution of Cancer

Author : Beata Ujvari,Benjamin Roche,Frederic Thomas
Publisher : Academic Press
Genre : Medical
Total View : 2083 Views
File Size : 47,8 Mb
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Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to ...

Atlas of Hematopathology

Atlas of Hematopathology

Author : Faramarz Naeim,P. Nagesh Rao,Sophie X. Song,Ryan T. Phan
Publisher : Academic Press
Genre : Science
Total View : 621 Views
File Size : 49,5 Mb
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Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches, Second Edition, will appeal to both a wide range of people undergoing training in a variety of medical fields and practicing non-hematopathologists. For clinicians, fellows and residents, correct diagnosis (and therefore correct treatment) of diseases depends on a strong understanding of ...