Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles
  • Author : Peter Gill
  • Release Date : 10 June 2020
  • Publisher : Academic Press
  • Genre : Law
  • Pages : 530
  • ISBN 13 : 9780128205686

Forensic Practitioner's Guide to the Interpretation of Complex DNA Profiles Book Summary

Over the past twenty years, there’s been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting ‘probabilistic genotyping’ to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range of technologies are used to interpret DNA profiles and the software approaches advocated are commonly used throughout the world. Forensic Practitioner’s Guide to the Interpretation of Complex DNA Profiles places the main concepts of DNA profiling into context and fills a niche that is unoccupied in current literature. The book begins with an introduction to basic forensic genetics, covering a brief historical description of the development and harmonization of STR markers and national DNA databases. The laws of statistics are described, along with the likelihood ratio based on Hardy-Weinberg equilibrium and alternative models considering sub-structuring and relatedness. The historical development of low template mixture analysis, theory and practice, is also described, so the reader has a full understanding of rationale and progression. Evaluation of evidence and statement writing is described in detail, along with common pitfalls and their avoidance. The authors have been at the forefront of the revolution, having made substantial contributions to theory and practice over the past two decades. All methods described are open-source and freely available, supported by sets of test-data and links to web-sites with further information. This book is written primarily for the biologist with little or no statistical training. However, sufficient information will also be provided for the experienced statistician. Consequently, the book appeals to a diverse audience Covers short tandem repeat (STR) analysis, including database searching and massive parallel sequencing (both STRs and SNPs) Encourages dissemination and understanding of probabilistic genotyping by including practical examples of varying complexity Written by authors intimately involved with software development, training at international workshops and reporting cases worldwide using the methods described in this book

Forensic Practitioner s Guide to the Interpretation of Complex DNA Profiles

Forensic Practitioner s Guide to the Interpretation of Complex DNA Profiles

Author : Peter Gill,Øyvind Bleka,Oskar Hansson,Corina Benschop,Hinda Haned
Publisher : Academic Press
Genre : Law
Total View : 7906 Views
File Size : 52,8 Mb
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Over the past twenty years, there’s been a gradual shift in the way forensic scientists approach the evaluation of DNA profiling evidence that is taken to court. Many laboratories are now adopting ‘probabilistic genotyping’ to interpret complex DNA mixtures. However, current practice is very diverse, where a whole range ...

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Publisher : CRC Press
Genre : Law
Total View : 9104 Views
File Size : 42,5 Mb
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The use of DNA profiling in forensic cases has been considered the most innovative technique in forensic science since fingerprinting, yet for those with limited scientific knowledge, understanding DNA enough to utilize it properly can be a daunting task. Introduction to Forensic DNA Evidence for Criminal Justice Professionals is designed ...

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Publisher : National Academies Press
Genre : Science
Total View : 5942 Views
File Size : 44,9 Mb
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In 1992 the National Research Council issued DNA Technology in Forensic Science, a book that documented the state of the art in this emerging field. Recently, this volume was brought to worldwide attention in the murder trial of celebrity O. J. Simpson. The Evaluation of Forensic DNA Evidence reports on developments ...