DNA Damage, DNA Repair and Disease
  • Author : Miral Dizdaroglu
  • Release Date : 19 November 2020
  • Publisher : Royal Society of Chemistry
  • Genre : Science
  • Pages : 480
  • ISBN 13 : 9781839162565

DNA Damage, DNA Repair and Disease Book Summary

The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA lesions and DNA repair mechanisms showed the involvement of DNA damage and DNA repair in the pathogenesis of many human diseases, most notably cancer. These books provide a comprehensive overview of the interdisciplinary area of DNA damage and DNA repair, and their relevance to disease pathology. Edited by recognised leaders in the field, this two-volume set is an appealing resource to a variety of readers including chemists, chemical biologists, geneticists, cancer researchers and drug discovery scientists.

DNA Damage  DNA Repair and Disease

DNA Damage DNA Repair and Disease

Author : Miral Dizdaroglu,R Stephen Lloyd
Publisher : Royal Society of Chemistry
Genre : Science
Total View : 6302 Views
File Size : 45,9 Mb
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The DNA of all organisms is constantly being damaged by endogenous and exogenous sources. Oxygen metabolism generates reactive species that can damage DNA, proteins and other organic compounds in living cells. Exogenous sources include ionizing and ultraviolet radiations, carcinogenic compounds and environmental toxins among others. The discovery of multiple DNA ...

DNA Damage and Repair

DNA Damage and Repair

Author : A. Castellani
Publisher : Springer Science & Business Media
Genre : Science
Total View : 9924 Views
File Size : 48,5 Mb
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The First International Congress on DNA Damage and Repair was held in Rome, Italy, July 12-17, 1987. It was organized by the Italian Com mission for Nuclear Alternative Energy Sources. The subject of DNA damage and repair involves almost all the fields ofbidogical sciences. Some of the more prominent ones include ...

DNA Repair and Mutagenesis

DNA Repair and Mutagenesis

Author : Errol C. Friedberg,Graham C. Walker,Wolfram Siede,Richard D. Wood
Publisher : American Society for Microbiology Press
Genre : Science
Total View : 8612 Views
File Size : 45,5 Mb
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An essential resource for all scientists researching cellular responses to DNA damage. • Introduces important new material reflective of the major changes and developments that have occurred in the field over the last decade. • Discussed the field within a strong historical framework, and all aspects of biological responses to DNA damage ...

New Research Directions in DNA Repair

New Research Directions in DNA Repair

Author : Clark Chen
Publisher : BoD – Books on Demand
Genre : Medical
Total View : 6994 Views
File Size : 50,7 Mb
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This book is intended for students and scientists working in the field of DNA repair. Select topics are presented here to illustrate novel concepts in DNA repair, the cross-talks between DNA repair and other fundamental cellular processes, and clinical translational efforts based on paradigms established in DNA repair. The book ...

DNA Repair and Cancer

DNA Repair and Cancer

Author : Srinivasan Madhusudan,David M. Wilson III
Publisher : CRC Press
Genre : Medical
Total View : 9138 Views
File Size : 40,6 Mb
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DNA repair is a rapidly advancing field in biology and these systems represent a major defense mechanism against environmental and intracellular damaging agents such as sunlight, ionizing radiation, and reactive oxygen species. With contributions from eminent researchers, this book explores the basics and current trends in this critical field. Topics ...

Free Radical Induced DNA Damage and Its Repair

Free Radical Induced DNA Damage and Its Repair

Author : Clemens Sonntag
Publisher : Springer Science & Business Media
Genre : Science
Total View : 6448 Views
File Size : 49,5 Mb
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The free-radical chemistry of DNA had been discussed in some detail in 1987 in my book The Chemical Basis of Radiation Biology. Obviously, the more recent developments and the concomitant higher level of understanding of mechanistic details are missing. Moreover, in the living cell, free-radical DNA damage is not only induced ...

Advances in DNA Damage and Repair

Advances in DNA Damage and Repair

Author : Miral Dizdaroglu,Ali Esat Karakaya
Publisher : Springer Science & Business Media
Genre : Science
Total View : 2477 Views
File Size : 48,6 Mb
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In recent years the field of DNA repair has flourished due to new findings on DNA repair mechanisms and the molecular basis of cancer. This volume covers the most recent developments in this research field and contains contributions from scientists working in various fields....