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Carbonic Anhydrases as Biocatalysts
  • Author : Claudiu T Supuran
  • Release Date : 14 January 2015
  • Publisher : Elsevier
  • Genre : Technology & Engineering
  • Pages : 398
  • ISBN 13 : 9780444632630
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Carbonic Anhydrases as Biocatalysts Book Summary

Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both medicine and biotechnology. Offers comprehensive coverage of the carbonic anhydrases enzyme family and their properties as biocatalysts Includes current applications of carbonic anhydrases in biotechnology on the basis of their catalytic efficiency, including new technologies for CO2 capture processes Identifies new targets for drug design studies Provides a selectivity profile for the different carbonic anhydrases and their related biomedical applications

Carbonic Anhydrases as Biocatalysts

Carbonic Anhydrases as Biocatalysts

Author : Claudiu T Supuran,Giuseppina De Simone
Publisher : Elsevier
Genre : Technology & Engineering
Total View : 4025 Views
File Size : 44,9 Mb
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Carbonic anhydrases (CAs, EC 4.2.1.1) are ubiquitous metalloenzymes, present throughout most living organisms and encoded by five evolutionarily unrelated gene families. The Carbonic Anhydrases as Biocatalysts: From Theory to Medical and Industrial Applications presents information on the growing interest in the study of this enzyme family and their applications to both ...

The Carbonic Anhydrases

The Carbonic Anhydrases

Author : W.R. Chegwidden,N.D. Carter,Y.H. Edwards
Publisher : Birkhäuser
Genre : Science
Total View : 7565 Views
File Size : 49,5 Mb
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Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ß, ?), ...

Carbonic Anhydrases

Carbonic Anhydrases

Author : Claudiu T. Supuran,Alessio Nocentini
Publisher : Academic Press
Genre : Science
Total View : 6683 Views
File Size : 52,6 Mb
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Carbonic Anhydrases provides an interdisciplinary review of the burgeoning carbonic anhydrase (CA) research area, spanning from CAs classification (biochemical and structural features) to drug design and pharmacology of CA inhibitors and activators, finally touching on the biotechnological applications of these metalloenzymes. The book adopts a clear step-by-step approach and introduction ...

Carbonic Anhydrase Mechanism Regulation Links to Disease and Industrial Applications

Carbonic Anhydrase Mechanism Regulation Links to Disease and Industrial Applications

Author : Susan C. Frost,Robert McKenna
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 6044 Views
File Size : 51,6 Mb
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The study of carbonic anhydrase has spanned multiple generations of scientists. Carbonic anhydrase was first discovered in 1932 by Meldrum and Roughton. Inhibition by sulfanilamide was shown in 1940 by Mann and Keilin. Even Hans Krebs contributed to early studies with a paper in 1948 showing the relationship of 25 different sulfonamides to CA ...

The Carbonic Anhydrases Current and Emerging Therapeutic Targets

The Carbonic Anhydrases Current and Emerging Therapeutic Targets

Author : W. Richard Chegwidden,Nicholas D. Carter
Publisher : Springer Nature
Genre : Medical
Total View : 1433 Views
File Size : 47,6 Mb
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This volume assembles and integrates the wealth of diverse information that is now accumulating in this burgeoning field. The existing and potential therapeutic applications of targeting CA cover a remarkably wide-range of diseases and disorders and have generated increasing and extensive interest in recent years. Its inter-disciplinary approach embraces both ...

The Carbonic Anhydrases

The Carbonic Anhydrases

Author : W.R. Chegwidden,N.D. Carter,Y.H. Edwards
Publisher : Springer Science & Business Media
Genre : Medical
Total View : 3799 Views
File Size : 51,6 Mb
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Carbonic anhydrase (CA) is a seemingly ubiquitous enzyme of profound physiological importance, which plays essential roles in respiration, acid-base homeostasis, bone resorption, calcification, photosynthesis, several biosynthetic pathways and a variety of processes involving ion, gas and fluid transfer. This enzyme, which is present in at least three gene families (a, ß, ?), ...

Carbonic Anhydrases and Metabolism

Carbonic Anhydrases and Metabolism

Author : Claudiu T. Supuran
Publisher : MDPI
Genre : Science
Total View : 126 Views
File Size : 45,9 Mb
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Carbonic anhydrases (CAs; EC 4.2.1.1) are metalloenzymes present in all kingdoms of life, as they equilibrate the reaction between three simple but essential chemical species: CO2, bicarbonate, and protons. Discovered more than 80 years ago, in 1933, these enzymes have been extensively investigated due to the biomedical application of their inhibitors, but also ...

The Carbonic Anhydrases

The Carbonic Anhydrases

Author : N.D. Carter,S.J. Dodgson,G. Gros,R.E. Tashian
Publisher : Springer Science & Business Media
Genre : Science
Total View : 8602 Views
File Size : 51,9 Mb
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As we approach the twenty-first century the problems of industrialization are evident: we find there is a greenhouse effect, the ozone layer is being depleted, the rain is acidified, and there is a terrible problem of increasing C0 concentrations in the atmo 2 sphere. The carbonic anhydrases are a unique family ...