Antimalarial Agents
  • Author : Graham L. Patrick
  • Release Date : 30 May 2020
  • Publisher : Elsevier
  • Genre : Science
  • Pages : 622
  • ISBN 13 : 9780081012413

Antimalarial Agents Book Summary

Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work towards antimalarial solution, providing practical guidance on current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world’s population. Advances over the last decade have seen vast improvements in the effectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential. Beginning with a focus on biological aspects of malaria, this book highlights the lifecycle of the parasite responsible for malaria, the problem of resistance, genetic mapping of the parasite’s genome, established drug targets, and potential drug targets for the future. The book also includes detailed study of the medicinal chemistry of antimalarial agents and a focus on the design of antimalarial drugs. Drawing on the knowledge of its expert authors and coupling historic research with current findings to provide a full picture of both past and current milestones, Antimalarial Agents: Design and Mechanism of Action is a comprehensive yet accessible guide for all those involved in the design, development and administration of antimalarial drugs, including academic researchers, medicinal chemists, malaria researchers and pharmaceutical scientists. Consolidates both past and current developments in the discovery and design of antimalarial drugs Presents content in a style that is both thorough and engaging, providing a supportive and guiding reference to students and researchers from interdisciplinary backgrounds Highlights drug targets currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected

Antimalarial Agents

Antimalarial Agents

Author : Graham L. Patrick
Publisher : Elsevier
Genre : Science
Total View : 6415 Views
File Size : 44,7 Mb
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Antimalarial Agents: Design and Mechanism of Action seeks to support medicinal chemists in their work towards antimalarial solution, providing practical guidance on current developments and highlighting promising leads for the future. Malaria is a deadly disease which threatens half of the world’s population. Advances over the last decade have ...

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Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
Genre : Medical
Total View : 1496 Views
File Size : 44,5 Mb
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Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of ...

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Publisher : National Academies Press
Genre : Medical
Total View : 680 Views
File Size : 55,6 Mb
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For more than 50 years, low-cost antimalarial drugs silently saved millions of lives and cured billions of debilitating infections. Today, however, these drugs no longer work against the deadliest form of malaria that exists throughout the world. Malaria deaths in sub-Saharan Africaâ€"currently just over one million per yearâ€"are rising ...

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Publisher : National Academies Press
Genre : Medical
Total View : 6370 Views
File Size : 47,9 Mb
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Author : Centers for Disease Control and Prevention CDC
Publisher : Oxford University Press
Genre : Medical
Total View : 378 Views
File Size : 45,5 Mb
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THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel has never been greater. For both international travelers and the health professionals who care for them, ...

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Publisher : National Academies Press
Genre : Medical
Total View : 3400 Views
File Size : 46,9 Mb
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Admittedly, the world and the nature of forced migration have changed a great deal over the last two decades. The relevance of data accumulated during that time period can now be called into question. The roundtable and the Program on Forced Migration at the Mailman School of Public Health of ...

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Author : Youyou Tu
Publisher : Unknown
Genre : Uncategorized
Total View : 8350 Views
File Size : 47,6 Mb
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From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief ...

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Publisher : Elsevier
Genre : Health & Fitness
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File Size : 42,8 Mb
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Medicinal Chemistry, Volume 12: Antimalarial Agents: Chemistry and Pharmacology presents the essentials of both biology and chemistry pertinent to the chemotherapy of malaria. This book discusses the nature of the disease, the physiology and biochemistry of the plasmodia, and the mode of action of drugs. Organized into 19 chapters, this volume begins ...